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Chapters
- 00:05Title
- 00:52Submandibular Salivary Gland Cannulation
- 03:32Submandibular Gland Instillation
- 04:40Submandibular Gland Localized Fractionated Irradiation
- 05:35Results: Representative Effect of Fractionated Radiation on Submandibular Gland Function
- 06:34Conclusion
Salivary gland hypofunction, a major adverse effect of head and neck radiotherapy diminishes a patient's quality of life. The demonstration of efficacy of new therapies in animal models is a prerequisite before clinical transition. This protocol describes retroductal administration and local irradiation of rat submandibular glands.
