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Chapters
- 00:05Title
- 01:00Instrument Preparation
- 02:36Anterior Chamber Cannulation
- 05:39Results: Retinal I/R Induces Neuronal Cell Death in the Ganglion Cell Layer and Impairs Retinal Neuron Function
- 06:30Conclusion
This article describes a procedure for inducing retinal ischemia-reperfusion injury by elevated intraocular pressure in mice. Retinal ischemia-reperfusion injury by elevated intraocular pressure serves to model human pathologies characterized by compromised oxygen and nutrient delivery in the retina, enabling researchers to examine potential cellular mechanisms and treatments for human diseases of the retinal neurovascular unit.
