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Chapters
- 00:05Title
- 01:43Villous Cytotrophoblast Isolation
- 05:51Trophoblast Purification
- 08:25In Vitro Induction of Normoxia and Hypoxia/reoxygenation
- 09:24Results: Anti-oxidant Effect of Melatonin in Syncytiotrophoblast Exposed to Hypoxia/reoxygenation
- 10:47Conclusion
This manuscript presents a unique in vitro model of immunopurified human villous cytotrophoblast cells cultured under hypoxia/reoxygenation. This model is suitable to study the protective effects of promising treatments, such as melatonin, on pregnancy complications associated with increased oxidative stress and altered placental function.
