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A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform
 

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform

Article DOI: 10.3791/54298-v 09:35 min July 16th, 2016
July 16th, 2016

챕터

요약

Critical challenges for the diabetes research field are to understand the molecular mechanisms that regulate islet β-cell replication and to develop methods for stimulating β-cell regeneration. Herein a high-content screening method to identify and assess the β-cell replication-promoting activity of small molecules is presented.

Tags

Keywords: In Vitro Pancreatic Islet β-cell Replication Screening Platform Beta Cell Biology Regenerative Therapy Diabetes Pancreatic Digestion Collagenase Tissue Sieve
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