Journal
/
/
Конструкция и использование низкой стоимости, Автоматизированная Morbidostat для адаптивной эволюции бактерий в Антибиотик Выбор лекарственных средств
JoVE 신문
유전학
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.  전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
JoVE 신문 유전학
Design and Use of a Low Cost, Automated Morbidostat for Adaptive Evolution of Bacteria Under Antibiotic Drug Selection
DOI:

10:50 min

September 27, 2016

, , ,

Chapters

  • 00:05Title
  • 00:46Assembly of the Morbidostat
  • 04:13Pretesting and Running the Morbidostat
  • 06:23On the Chip Growth Experiment
  • 07:38Results: Evolution of Antibiotic Drug Resistance using a Morbidostat
  • 09:31Conclusion

Summary

자동 번역

We describe a low cost, configurable morbidostat that enables the characterization of antibiotic drug resistance by dynamically adjusting the drug concentration. The device can be integrated with a multiplexed microfluidic platform. The approach can be scaled up for laboratory antibiotic drug resistance studies.

Related Videos

Read Article