JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
1Department of Surgery,University of Maryland School of Medicine, 2Department of Medicine,University of Maryland School of Medicine, 3Department of Radiology,University of Maryland School of Medicine, 4Food and Drug Administration, 5Department of Pharmaceutical Sciences,University of Maryland School of Pharmacy, 6VA Maryland Health Care System
Chapters
- 00:05Title
- 00:5919F-Labeled Bile Acid Gavage, Organ Harvest and Bile Acid Measurement
- 04:02Live Animal Proton (1H) and Fluorine (19F) Magnetic Resonance Imaging (MRI)
- 05:51Results: Representative Multi-fluorinated Bile Acid (MFBA) Measurement in the Mouse Gallbladder
- 07:51Conclusion
Verktøy for å diagnostisere gallesyre malabsorpsjon og måle gallesyre transport in vivo er begrenset. En innovativ tilnærming i levende dyr er beskrevet som bruker kombinerte proton (1 H) pluss fluor (19 F) magnetic resonance imaging; denne romanen metodikken har translasjonsforskning potensial til å screene for gallesyre malabsorpsjon i klinisk praksis.
