JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
Chapters
- 00:05Title
- 00:44Preparation of Silk Nanoparticles from Bombyx mori Cocoons
- 04:12Preparation of Doxorubicin-loaded Silk Nanoparticles
- 05:28In Vitro Cytotoxicity of Control and Doxorubicin-loaded Silk Nanoparticles
- 06:26Results: Characterization and In Vitro Cytotoxicity of Silk Nanoparticles and Doxorubicin-loaded Silk Nanoparticles
- 08:06Conclusion
Nanoparticles are emerging as promising drug delivery systems for a broad range of indications. Here, we describe a simple yet powerful method to manufacture silk nanoparticles using reverse engineered Bombyx mori silk. These silk nanoparticles can be readily loaded with a therapeutic payload and subsequently explored for drug delivery applications.
