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En sammenlignende undersøgelse af Drug Delivery Metoder Målrettede til Mouse indre øre: Bullostomy<em> Versus</em> Transtympanic Injection
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A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection

En sammenlignende undersøgelse af Drug Delivery Metoder Målrettede til Mouse indre øre: Bullostomy<em> Versus</em> Transtympanic Injection

DOI:
10.3791/54951-v

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09:18 min

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March 08, 2017

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, , , , , ,
1Instituto de Investigaciones Biomédicas (IIBm) Alberto Sols CSIC-UAM, 2Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER),Instituto de Salud Carlos III (ISCIII), 3Instituto de Investigación Sanitaria La Paz (IdiPAZ), 4Facultad de Veterinaria,Universidad Complutense de Madrid, 5Departmento de Otorrino laringología,Hospital Universitario La Paz

Chapters

  • 00:05Title
  • 01:02Auditory Brainstem (ABR) Procedure
  • 03:20Bullostomy
  • 05:57Transtympanic Injection
  • 07:18Results: Maintenance of ABR and Morphology Following Bullostomy and Transtympanic Injection Procedures
  • 08:28Conclusion

Summary

자동 번역

자동 번역

Two microsurgery approaches for local drug delivery to the inner ear are described here and compared in terms of impact on hearing parameters, cochlear cytoarchitecture and expression of inflammatory markers.

Tags

Keywords: Drug DeliveryInner EarMouseBullostomyTranstympanic InjectionHearingCochlear CytoarchitectureAuditory FieldAnimal StudiesMinimally InvasiveHearing LossMicrosurgical ProceduresMiddle EarAnesthetized MouseABRAcoustic StimuliEvoked Response

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