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颈动脉肿瘤细胞注射，产生脑转移瘤小鼠模型

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Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis

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颈动脉肿瘤细胞注射，产生脑转移瘤小鼠模型

DOI:

10.3791/55085-v

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07:43 min

•

February 08, 2017

•

Chenyu Zhang, Frank J. Lowery, Dihua Yu

¹Department of Molecular and Cellular Oncology,The University of Texas MD Anderson Cancer Center

Chapters

00:05Title
00:56Prepare Cancer Cells for Injection
02:15Prepare Mice for Tumor Cell Injection
04:02Cancer Cell Injection into Carotid Artery
05:44Results: Non-invasive Monitoring for Brain Metastasis Outgrowth
06:25Conclusion

Summary

자동 번역

脑转移已成为迫切满足医疗需要，因为其发病率有增加，而治疗方法仍然治标不治本。经由颈动脉动脉注射癌细胞创建脑转移的实验动物模型有利于新型干预方案的疾病生物学和评价的机理研究。

Tags

Brain Metastasis Cancer Cell Injection Carotid Artery In Vivo Experimental Model Mouse Model Microsurgical Technique Reproducibility Therapeutic Efficacy Cell Culture Cell Harvesting Cell Resuspension Anesthesia Surgical Procedure Carotid Artery Isolation Blood Flow Occlusion

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