Waiting
로그인 처리 중...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Genetics / QTL Mapping and CRISPR/Cas9 Editing to Identify a …
JoVE Journal
Genetics

이 콘텐츠 오픈 액세스로 구독없이 시청하실 수 있습니다.

JoVE Journal Genetics
QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii
 

QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii

Article DOI: 10.3791/55185-v • 11:37 min • June 22nd, 2017
June 22nd, 2017 •
1, 2, 2
1State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, 2Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University

챕터

요약
Automatic Translation

Details are presented on how QTL mapping with a whole genome sequence based genetic map can be used to identify a drug resistance gene in Toxoplasma gondii and how this can be verified with the CRISPR/Cas9 system that efficiently edits a genomic target, in this case the drug resistance gene.

Tags

QTL Mapping CRISPR/Cas9 Editing Drug Resistance Gene Toxoplasma Gondii Quantitative Trait Locus Mapping Whole Genome Sequencing Genetic Manipulation Pathogens Pathogenesis Drug Resistance Parasite Solution HFF Cells Sinefungin Resistance Growth Phenotype
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter