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Cancer Research

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A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines
 

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines

Article DOI: 10.3791/55271-v 07:59 min March 4th, 2017
March 4th, 2017

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요약

The poor understanding of the in vivo performance of nanomedicines stymies their clinical translation. Procedures to evaluate the in vivo behavior of cancer nanomedicines at systemic, tissue, single-cell, and subcellular levels in tumor-bearing immunocompetent mice are described here. This approach may help researchers to identify promising cancer nanomedicines for clinical translation.

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Keywords: Cancer Nanomedicines In Vivo Performance Tumor-bearing Mice Dual-labeling Approach Liposomes Lipophilic Cationic Fluorescent Dye Phosphate-buffered Saline Dynamic Light Scattering Radiolabeling Zirconium-89 Oxalate Size-exclusion HPLC Radiochemical Purity
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