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胎児アルコール スペクトルの無秩序のモデルラットにおける海馬機能障害を評価するためにトレース瞬目反射条件づけの使用
JoVE 신문
신경과학
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JoVE 신문 신경과학
The Use of Trace Eyeblink Classical Conditioning to Assess Hippocampal Dysfunction in a Rat Model of Fetal Alcohol Spectrum Disorders
DOI:

19:57 min

August 05, 2017

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Chapters

  • 00:00Title
  • 01:02Neonatal Alcohol Exposure
  • 02:53Eyelid Surgery
  • 02:56Eyelid Surgery: Materials and Setup
  • 03:13Eyelid Surgery: Animal Preparation
  • 03:50Eyelid Surgery: Surgery
  • 09:34Trace Eyeblink Classical Conditioning
  • 09:37Trace Eyeblink Classical Conditioning: Animal Preparation and System Setup
  • 10:40Trace Eyeblink Classical Conditioning: Animal Status Check
  • 11:08Trace Eyeblink Classical Conditioning: Explantation of Trace ECC Procedure
  • 15:00Trace Eyeblink Classical Conditioning: Software Setup and Begin Testing
  • 15:44Trace Eyeblink Classical Conditioning: Live Recording: Unintubated-control Rat Session 1 Trial 15
  • 15:57Trace Eyeblink Classical Conditioning: Replay at 0.30x Speed
  • 16:14Trace Eyeblink Classical Conditioning: Progression of Training Through Six Sessions
  • 16:36Trace Eyeblink Classical Conditioning: Development of Adaptive CRs
  • 16:46Trace Eyeblink Classical Conditioning: Live Recording: Unintubated-control Rat Session 6 Trial 96
  • 16:58Trace Eyeblink Classical Conditioning: Replay at 0.30x Speed
  • 17:18Trace Eyeblink Classical Conditioning: Live Recording: Alcohol-intubated-control Rat Session 6 Trial 100
  • 17:35Representative Results
  • 19:00Conclusion

Summary

자동 번역

トレース瞬目反射条件づけ (ECC) を用いて評価したラット海馬依存学習投与早期新生児の脳の発達の中にアルコールの高濃度 (11.9 %v/v)。一般的には、ECC プロシージャは、多くの心理的な医学の設定の間で脳機能障害を検出するため音の診断ツールです。

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