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Chapters
- 00:05Title
- 00:55Dosator Assembly, Filling and Actuation
- 02:39Results: Representative Pharmacokinetic Evaluation via Passive Inhalation
- 03:38Conclusion
During development of drugs for pulmonary delivery, it is necessary to evaluate pharmacokinetics and efficacy in an animal model. We present a method to build a disposable aerosol dispersion system from of-the-shelf components that can be used to administer intrapulmonary dry powder aerosol to rodents.
Tags
Disposable DosatorPulmonary InsufflationTherapeutic AgentsSmall AnimalsDry Powder AerosolAerosol Dispersion SystemAerosol SciencePharmacokineticsEfficacy TestingPolypropylene Microcentrifuge TubeStainless Steel Wire ClothAnalytical MicrobalanceSyringeDosing PortExposure ChamberAcrylic Dosing Chamber
