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A Novel Method to Model Chronic Traumatic Encephalopathy in Drosophila
 

A Novel Method to Model Chronic Traumatic Encephalopathy in Drosophila

Article DOI: 10.3791/55602-v 10:15 min July 4th, 2017
July 4th, 2017

챕터

요약

Here, we describe a new approach to inflict closed-head traumatic brain injury in Drosophila melanogaster. Our method has the advantage of directly delivering repetitive impacts with adjustable strength to the head alone. Further exploration of the invertebrate system will help to illuminate the pathogenesis of chronic traumatic encephalopathy.

Tags

Keywords: Chronic Traumatic Encephalopathy Drosophila Closed Traumatic Brain Injury Neuron Degeneration Impactor Fly Holder Carbon Dioxide Anesthesia
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