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1Department of Medicine, Case Cardiovascular Research Institute,Case Western Reserve University, 2Harrington Heart and Vascular Institute,University Hospitals Cleveland Medical Center, 3Institute for Transformative Molecular Medicine, Case Western Reserve University School of Medicine,University Hospitals Cleveland Medical Center
Chapters
- 00:05Title
- 01:13Ileectomy, Anastomosis, and Ileectomy-induced Bile Overaccumulation Evaluation
- 04:31Results: Representative Ileectomy-induced Bile Overaccumulation Analysis
- 06:09Conclusion
Small intestine-dependent bile acid reabsorption and feedback inhibition of hepatic bile acid synthesis is important for systemic homeostasis and health. In this study, we describe a mouse model for ileal resection to evaluate ileectomy-induced bile malabsorption, overaccumulation, and toxicity in mouse intestine.
