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Chapters
- 00:05Title
- 00:51Preparation of Samples and NMR Instrument for 19F TD-NMR Measurement
- 01:56Measurement of the T1 or Longitudinal Relaxation Time for Standard Pure API Samples
- 03:23Measuring Calibration Samples with Pure API
- 04:29Measuring Drug Product Samples as Tablets
- 04:59Generation of Calibration Curves with Pure API Samples and Adding the Data from Drug Product Samples as Tablets in the Calibration Curve
- 06:59Calculation of the Fluorinated API Drug Weight in the Formulated Drug Product Using the Calibration Curves
- 07:33Results: Evaluation of the Average Drug Content of Cinacalcet in Tablet Dosage Forms by Low-field Fluorine-19 Time-domain Nuclear Magnetic Resonance
- 08:29Conclusion
कम क्षेत्र फ्लोरीन-19 (19F) समय-डोमेन (TD) नाभिकीय चुंबकीय अनुनाद (एनएमआर) का उपयोग करके तैयार किए गए औषध उत्पादों में मादक पदार्थों की औसत सामग्री के उपाय करने वाली एक सरल और गैर-विनाशकारी तकनीक यहां प्रस्तुत की गई है । दवा उद्योग में दवाओं के विकास और विनिर्माण के लिए तकनीक को लागू किया जा सकता है ।
