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Immunology and Infection

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JoVE Journal Immunology and Infection
En metode til at vurdere Fc-medieret effektor funktion induceret af Influenza Hemagglutinin specifikke antistoffer
 
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En metode til at vurdere Fc-medieret effektor funktion induceret af Influenza Hemagglutinin specifikke antistoffer

Article DOI: 10.3791/56256-v • 04:47 min • February 23rd, 2018
February 23rd, 2018 •
1,2, 1, 1,2, 3
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, 2Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 3Department of Infectious Disease, J. Craig Venter Institute

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Vi beskriver en metode til at måle aktivering af Fc-medieret effektor funktion af antistoffer der er rettet mod influenza virus hemagglutinin. Denne analyse kan også tilpasses for at vurdere monoklonale antistoffer eller polyklonale sera rettet mod andre virale overflade glykoproteiner evne til at fremkalde Fc-medieret immunitet.

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Immunologi sag 132,
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