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Immunology and Infection

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JoVE Journal Immunology and Infection
Imaging Mycobacterium tuberkulose i mus med Reporter enzym fluorescens
 
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Imaging Mycobacterium tuberkulose i mus med Reporter enzym fluorescens

Article DOI: 10.3791/56801-v • 10:06 min • February 26th, 2018
February 26th, 2018 •
*1, *2, 1, 1
1Department of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, 2Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health
* These authors contributed equally

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Vi beskriver den optiske billeddannelse af mus inficeret med Mycobacterium tuberculosis (M. tuberkulose) ved hjælp af reporter enzym fluorescens (REF). Denne protokol letter følsom og specifik påvisning af M. tuberkulose i prækliniske dyremodeller for patogenesen, therapeutics og vaccine forskning.

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Immunologi sag 132 pulmonal optisk lactamase vacciner dyremodeller therapeutics patogenese
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