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Chapters
- 00:04Title
- 00:50Status Epilepticus (SE) Induction
- 03:24Implantation Surgery for Video-EEG Monitoriing
- 06:19Video and EEG Monitoring and Analysis
- 08:01Results: Successful SE Can Induce Hippocampal Cell Death and SRS
- 09:03Conclusion
This manuscript describes a method of inducing status epilepticus by systemic pilocarpine injection and of monitoring spontaneous recurrent seizures in live animals using a wireless telemetry video and electroencephalogram system. This protocol can be utilized for studying the pathophysiologic mechanisms of chronic epilepsy, epileptogenesis, and acute seizures.
