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otx1 和 otx2 作为鼻窦癌和嗅觉神经母细胞瘤的两种可能的分子标记物的鉴定

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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

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otx1 和 otx2 作为鼻窦癌和嗅觉神经母细胞瘤的两种可能的分子标记物的鉴定

DOI:

10.3791/56880-v

•

07:00 min

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February 28, 2019

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Giovanni Micheloni*¹, Giorgia Millefanti*¹, Andrea Conti, Cristina Pirrone, Alessandro Marando, Alessia Rainero, Lucia Tararà, Andrea Pistochini, Francesco Lo Curto, Francesco Pasquali, Paolo Castelnuovo, Francesco Acquati, Annalisa Grimaldi, Roberto Valli, Giovanni Porta

¹Department of Medicine and Surgery,University of Insubria, ²Department of Surgical and Morphological Science,University of Insubria, ³Department of Biotechnology and Life Science,University of Insubria

Chapters

00:04Title
00:58Immunochemistry
03:03Real-time PCR and Data Analysis
04:56Results: Representative Images of OTX Immunohistochemical Expression in Control and Neoplastic Tissues
05:47Conclusion

Summary

자동 번역

同源基因是调节基因, 通常与成人生物中的肿瘤有关。我们通过免疫组织化学和实时 pcr 分析, 在正常和炎症性鼻黏膜和鼻窦肿瘤中研究了它们的比较表达, 以便将它们作为可能的诊断和治疗靶点。

Tags

Keywords: OTX1 OTX2 Sinonasal Carcinomas Olfactory Neuroblastomas Molecular Markers RNA Extraction Real-time PCR Immunohistochemistry FFPE Samples Antigen Retrieval Triton X Secondary Antibody ABC Peroxidase Diaminobenzene Hematoxylin Dehydration Probe-based PCR

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