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酶联反应合成 l-赖氨酸手性氨基醇的研究
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Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
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酶联反应合成 l-赖氨酸手性氨基醇的研究

DOI:
10.3791/56926-v

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09:14 min

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February 16, 2018

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, ,
1Génomique Métabolique, Genoscope, Institut François Jacob,CEA, CNRS, Univ Evry, Univ Paris-Saclay

Chapters

  • 00:04Title
  • 00:48Semi-preparative One-pot Biocatalytic Reaction, Reaction Monitoring, and Product Analysis
  • 03:17Semi-preparative One-pot Biocatalytic Reaction: Second and Third Steps
  • 06:01Results: Investigation of Pyridoxal Phosphate Dependent Decarboxylase (PLP DC) Activities towards Hydroxy Lysine Derivatives
  • 07:56Conclusion

Summary

자동 번역

자동 번역

手性氨基醇是在有机合成中用作支架的多功能分子。从 l-赖氨酸开始, 用酶催化的酶联反应合成氨基醇, 然后将相应羟基氨基酸的羧酸基团 diastereoselective羧.

Tags

Enzymatic Cascade ReactionsChiral Amino AlcoholsL-lysineChiral AuxiliariesPharmaceutical TherapyOne-pot ProcedureDeoxygenase KD-01DNFB DerivatizationHPLC AnalysisDeoxygenase KD-02Decarboxylase DccpinPLP

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