Journal
/
암 연구학
/
Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
JoVE 신문
암 연구학
This content is Free Access.
JoVE 신문 암 연구학
Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

DOI:
10.3791/57167-v

•

06:51 min

•

July 21, 2018

•

, , , , , , , ,
1Division of Pulmonary and Critical Care Medicine,University of California Los Angeles David Geffen School of Medicine, 2University of North Carolina at Chapel Hill, 3Department of Molecular and Medical Pharmacology,University of California Los Angeles, 4Andor Technology, 5Division of Orthopaedic Surgery,University of California Los Angeles David Geffen School of Medicine

Chapters

  • 00:04Title
  • 00:4718F-FDG PET and CT Imaging in Mice
  • 04:06Image Processing
  • 05:09Results: 18F-FDG PET Identifies Metabolically Active Lung Tumors
  • 06:16Conclusion

Summary

자동 번역

자동 번역

In this protocol, we describe how to utilize [18F]-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography (18F-FDG PET/CT) imaging to measure the tumor metabolic response to the targeted therapy MLN0128 in a Kras/Lkb1 mutant mouse model of lung cancer and coupled imaging with high resolution ex vivo autoradiography and quantitative histology.

Tags

Keywords: 18F-FDG PET/CTLung CancerTumor MetabolismCancer TherapeuticsQuantitative HistologyNon-invasive ImagingMouse Model

Article

Embed

플레이리스트에 추가

Usage Statistics

Related Videos

check_url/kr/57167?article_type=v

Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures
check_url/kr/57167?article_type=v

Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis
check_url/kr/57167?article_type=v

Utilizing High Resolution Ultrasound to Monitor Tumor Onset and Growth in Genetically Engineered Pancreatic Cancer Models
check_url/kr/57167?article_type=v

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models
check_url/kr/57167?article_type=v

Phosphopeptide Enrichment Coupled with Label-free Quantitative Mass Spectrometry to Investigate the Phosphoproteome in Prostate Cancer
check_url/kr/57167?article_type=v

Elastic Staining on Paraffin-embedded Slides of pT3N0M0 Gastric Cancer Tissue
check_url/kr/57167?article_type=v

Using Microarrays to Interrogate Microenvironmental Impact on Cellular Phenotypes in Cancer
check_url/kr/57167?article_type=v

A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
check_url/kr/57167?article_type=v

Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines
check_url/kr/57167?article_type=v

Perfusion and Inflation of the Mouse Lung for Tumor Histology

Read Article