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Chapters
- 00:05Title
- 01:02Vector Format Master Mold Formation
- 02:28Laser Cut the Acrylic Master Molds
- 03:47Preparing the PDMS Mold for Cell or Tissue Culture
- 05:30Casting Collagen and Fibrin Hydrogel Tissues
- 07:25Results: Mold Enhanced Alignment of Cardiac Tissue Constructs
- 08:22Conclusion
Herein we present a rapid, facile, and low-cost method for fabricating custom polydimethylsiloxane molds that can be used for producing hydrogel-based engineered tissues with complex geometries. We additionally describe results from mechanical and histological assessments conducted on engineered cardiac tissues produced using this technique.
