Journal
/
의학
/
A Closed-chest Model to Induce Transverse Aortic Constriction in Mice
JoVE 신문
의학
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.  전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
JoVE 신문 의학
A Closed-chest Model to Induce Transverse Aortic Constriction in Mice

A Closed-chest Model to Induce Transverse Aortic Constriction in Mice

DOI:
10.3791/57397-v

•

08:10 min

•

April 05, 2018

•

, , , , , , ,
1Department of Anaesthesiology,University Hospital Bonn, 2Department of Cardiac Surgery,University Hospital Bonn, 3Institute of Physiology 2,University of Bonn, 4Department of Medicine – Cardiology,University Hospital Bonn

Chapters

  • 00:04Title
  • 01:01Induction of Anesthesia and Intubation
  • 02:57Preoperative Doppler Measurement and Thoracotomy
  • 04:03Banding the Transverse Aorta
  • 05:58Results: Induction of Successful Transverse Aortic Constriction in Mice
  • 07:30Conclusion

Summary

자동 번역

자동 번역

Here, we present a protocol of Transverse Aortic constriction (TAC) via a lateral thoracotomy. This technique is a minimally invasive, closed chest surgical procedure aiming to simulate pressure overload and heart failure in mice utilizing standard TAC laboratory settings.

Tags

Transverse Aortic ConstrictionMurine Closed Chest ModelLeft Ventricular Myocardial HypertrophyMinimal Invasive TechniqueCardiac MacrophagiaRib CageSurgical TraumaAnesthesiaIntubationCarotid ArteriesDoppler Probe

Article

Embed

플레이리스트에 추가

Usage Statistics

Related Videos

The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice

A Murine Closed-chest Model of Myocardial Ischemia and Reperfusion

Ascending Aortic Constriction in Rats for Creation of Pressure Overload Cardiac Hypertrophy Model

A Rat Model of Ventricular Fibrillation and Resuscitation by Conventional Closed-chest Technique

A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice

Assessment of Cardiac Morphological and Functional Changes in Mouse Model of Transverse Aortic Constriction by Echocardiographic Imaging

Minimally Invasive Transverse Aortic Constriction in Mice

Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy

Improvement of a Closed Chest Porcine Myocardial Infarction Model by Standardization of Tissue and Blood Sampling Procedures

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

Read Article