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Chapters
- 00:05Title
- 00:55Construct-positive Glioblastoma Cell Sorting
- 02:46Near-infrared Fluorescent Protein (iRFP)-tagged Glioblastoma Cell Intracranial Injection
- 04:49Fluorescence Molecular Tomography (FMT) Imaging and Analysis
- 06:22Results: Representative In Vivo FMT Imaging of Glioblastoma Xenografts
- 07:27Conclusion
Orthotopic intracranial injection of tumor cells has been used in cancer research to study brain tumor biology, progression, evolution, and therapeutic response. Here we present fluorescence molecular tomography of tumor xenografts, which provides real-time intravital imaging and quantification of a tumor mass in preclinical glioblastoma models.
Tags
Fluorescence Molecular TomographyFMTGlioblastoma XenograftsIn Vivo ImagingBrain Tumor Biology암 연구학Drug DiscoveryTumor AggressivenessTumor HeterogeneityTreatment ResponsivenessNon-invasiveQuantitativeXenograft ModelsGlioblastoma CellsLentivirusFluorescent ProteinFlow CytometryCell SortingSingle Cell SuspensionPBSIn Vivo Experiments
