This content is Free Access.
1Department of Neurobiology, F. M. Kirby Neurobiology Center,Boston Children’s Hospital, Harvard Medical School, 2Proteomic Mass Spectrometry,Wellcome Trust Sanger Institute, Wellcome Genome Campus, 3Centre for Molecular Informatics, Department of Chemistry,University of Cambridge, 4Functional Proteomics Group, Chester Beatty Laboratories,Institute of Cancer Research
Chapters
- 00:05Title
- 00:51Mapping of Peptides using PoGoGUI
- 02:36Visualizing in the Integrative Genomics Viewer
- 03:57Mapping Peptides Identified Through a Custom Variant Database to a Reference Genome
- 04:44Mapping Peptides from Multiple Files Using PoGoGUI
- 05:48Generating a Track Hub from Mapped Peptides and Visualizing a Track Hub in the UCSC Genome Browser
- 06:50Results: Post-translational Modification and Varient Enabled Mapping of Peptides to Genomes
- 08:21Conclusion
Aqui apresentamos a ferramenta proteogenomic PoGo e protocolos para rápido, quantitativa, borne-translational modificação e variante habilitado para mapeamento de peptídeos identificados através de espectrometria de massa em genomas de referência. Esta ferramenta é útil para integrar e Visualizar proteogenomic e estudos pessoais proteomic interfaceando com dados de genómica ortogonais.
