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JoVE Journal Bioengineering
Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro modellsystemer indusere celle-formet formasjon
 
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Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro modellsystemer indusere celle-formet formasjon

Article DOI: 10.3791/57826-v • 16:20 min • July 2nd, 2018
July 2nd, 2018 •
*1, *2,3, 2, 4, 4, 3, 2,5
1Department of Mechanical Engineering, McGill University Montreal, 2Department of Bioengineering, McGill University Montreal, 3Department of Molecular Biology, Instituto Potosino de Investigación Científica y Tecnológica, A.C. (IPICyT), 4Department of Mining and Materials Engineering, McGill University Montreal, 5Department of Biomedical Engineering, McGill University Montreal
* These authors contributed equally

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Vi utviklet en heterogen bryst kreft modell består av udødeliggjort svulst og fibroblast celler i en bioprintable alginate/gelatin bioink. Modellen viser i vivo svulst microenvironment og forenkler dannelsen av flercellet svulst spheroids, gir innsikt i mekanismer kjøring tumorigenesis.

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Bioteknologi problemet 137 3D bioprinting hydrogel kreftcellene svulst spheroids alginate gelatin
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