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1Wallace H. Coulter Department of Biomedical Engineering,Georgia Tech College of Engineering and Emory School of Medicine, 2Parker H. Petit Institute of Bioengineering and Bioscience, 3Institute for Electronics and Nanotechnology,Georgia Tech, 4Integrated Cancer Research Center,Georgia Tech, 5The Georgia Immunoengineering Consortium,Emory University and Georgia Tech
Chapters
- 00:04Title
- 00:36Iron Oxide Nanoparticle (IONP) Synthesis
- 05:22Peptide Design, Conjugation to Iron Oxide Nanoparticles, and In Vitro Validation
- 07:10Administration of Nanosensors and Urine Detection of Cancer
- 08:18Results: Detecting Protease Activity
- 09:52Conclusion
Proteasen sind streng regulierte Enzyme grundlegende biologische Prozesse und Dysregulated Protease-Aktivität Laufwerke Fortschreiten von komplexen Krankheiten wie Krebs beteiligt. Diese Methode soll Nanosensoren geschaffen, die Protease-Aktivität in Vivo durch die Herstellung einer Spaltung Signal, das vom Host Urin nachweisbar ist und Krankheit diskriminiert messen.
