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Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model
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JoVE 신문 의학
Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model
DOI:

05:08 min

February 17, 2019

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Chapters

  • 00:04Title
  • 00:57Pluripotent Stem Cell (PSC) Transplantation, Bioluminescence Imaging (BLI), and Teratoma Irradiation
  • 03:48Results: Representative Successful Tumor Induction and Treatment
  • 04:25Conclusion

Summary

자동 번역

Research on treatment strategies for pluripotent stem cell-derived teratomas is important for the clinical translation of stem cell therapy. Here, we describe a protocol to, first, generate stem cell-derived teratomas in mice and, then, to selectively target and treat these tumors in vivo using a small-animal irradiator.

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