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利用外束辐射对小型动物模型的多能干细胞衍生畸胎瘤进行靶向选择性治疗
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Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model
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利用外束辐射对小型动物模型的多能干细胞衍生畸胎瘤进行靶向选择性治疗

DOI:
10.3791/58115-v

•

05:08 min

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February 17, 2019

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, , , , , ,
1Stanford Cardiovascular Institute,Stanford University School of Medicine, 2Department of Medicine, Division of Cardiology,Stanford University School of Medicine, 3Medical Service, Cardiology Section,Veteran Affairs Palo Alto Health Care System, 4Department of Pathology,Stanford University School of Medicine, 5Department of Radiology, Molecular Imaging Program,Stanford University School of Medicine, 6Peking University Shenzhen Health Science Institute, 7Department of Radiation Oncology,Stanford University School of Medicine

Chapters

  • 00:04Title
  • 00:57Pluripotent Stem Cell (PSC) Transplantation, Bioluminescence Imaging (BLI), and Teratoma Irradiation
  • 03:48Results: Representative Successful Tumor Induction and Treatment
  • 04:25Conclusion

Summary

자동 번역

자동 번역

多能干细胞衍生畸胎瘤治疗策略的研究对干细胞治疗的临床翻译具有重要意义。在这里, 我们描述了一种协议, 首先, 在小鼠体内产生干细胞衍生的畸胎瘤, 然后, 选择性地靶向和治疗这些肿瘤在体内使用一个小动物辐照器。

Tags

Stem CellTeratomaExternal Beam RadiationSmall Animal ModelIPSCsBioluminescence ImagingMatrigelAthymic Nude MiceCell TherapyTargeted Treatment

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