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Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
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Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides

DOI:
10.3791/58135-v

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09:54 min

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August 20, 2018

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, ,
1Department of Chemistry and Biochemistry,Fairfield University

Chapters

  • 00:04Title
  • 00:421,2-Dithiolane Modified Peptide Synthesis and Purification
  • 02:51Solid-Phase Peptide Synthesis (SPPS) and On-Resin Dithiolane Precursor Coupling and Thioacetate Deprotection and Peptide-Resin Cleavage
  • 04:571,2-Dithiolane Modified Peptide Purification and Amyloid Fiber Formation
  • 06:31Spectroscopic Amyloid Fiber Characterization and Amyloid Fiber Microscopy
  • 08:13Results: 1,2-Dithiolane Modified Peptide Supramolecular Characterization
  • 09:23Conclusion

Summary

자동 번역

자동 번역

A protocol for the synthesis of a 1,2-dithiolane modified peptide and the characterization of the supramolecular structures resulting from the peptide self-assembly.

Tags

Keywords: 12-dithiolaneSelf-assembling PeptidesSupermolecular StructuresPeptide SynthesisOrganic SynthesisCharacterizationReaction MonitoringThin-layer ChromatographyExtractionCoupling Reaction

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