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1Laboratory for Reproductive Health, Institute of Biomedicine and Biotechnology,Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences (CAS), 2Guangdong Key Laboratory of Nanomedicine, CAS Key Lab for Health Informatics,Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences (CAS), 3Department of Chemistry,Guangdong Medical University
Chapters
- 00:04Title
- 00:35Synthesis of DNPs
- 01:34Conjugation of Peptides to DNPs
- 02:54Fluorescence Microscopy Assessment of pICSA-Targeted Nanoparticle Uptake in Choriocarcinoma (JEG3) Cells
- 04:18Results: Characterization and Cellular Uptake of plCSA-DNPs
- 05:12Conclusion
Nous présentons ici un protocole pour la synthèse de peptide de liaison placentaire chondroïtine sulfate A (plCSA-BP)-conjugués de lipide-polymère nanoparticules via seule étape sonication et bioconjugate techniques. Ces particules constituent un nouvel outil pour l’administration ciblée d’agents thérapeutiques tumeurs plus humaines et les trophoblastes placentaires pour traiter des cancers et des troubles placentaires.
