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一种新的脑外伤体损伤模型
JoVE 신문
신경과학
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JoVE 신문 신경과학
A Novel In Vitro Model of Blast Traumatic Brain Injury
DOI:

08:59 min

December 21, 2018

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Chapters

  • 00:04Title
  • 00:38Preparation of Hippocampal Organotypic Slices for the Experimental Blast TBI Protocol
  • 02:39Submersion and Transport of Tissue Culture Inserts with Hippocampal Organotypic Slices
  • 03:44Preparation of the Shock Tube and Hippocampal Organotypic Slice Shock Wave Exposure
  • 07:05Results: Typical Shockwave and Resulting Injury in Organotypic Hippocampal Slice
  • 08:11Conclusion

Summary

자동 번역

本文介绍了一种新的原发性爆炸创伤性脑损伤模型。压缩空气驱动的激波管被用来暴露在体外小鼠海马切片培养器的单个冲击波。这是一个简单而快速的协议, 产生可重复的脑组织损伤, 具有较高的吞吐量。

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