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1Department of Pharmacology and Toxicology,The University of Mississippi Medical Center, 2Department of Medicine, Division of Nephrology,Rush University Medical Center, 3Department of Medicine, Division of Nephrology,The University of Mississippi Medical Center, 4Department of Neurology,The University of Mississippi Medical Center
Chapters
- 00:04Title
- 01:34Kidney Isolation
- 02:33Kidney Homogenization, Incubation, and Straining
- 05:10Glomeruli Enumeration and Nephron Number Extrapolation
- 06:20Results: Representative Nephron Quantification
- 07:11Conclusion
Las estimaciones del número total de Nefrona renal son importantes clínicamente y experimentalmente, ya que existe una Asociación inversa entre el número de Nefrona y un mayor riesgo de enfermedad renal y cardiovascular. En este documento, se demuestra el uso del método de maceración ácida, que proporciona estimaciones rápidas y fiables del número total de Nefrona renal.
