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爆炸性神经损伤对压生啮鼠中脑动脉的影响

JoVE 신문
신경과학

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JoVE 신문 신경과학

Effects of Blast-induced Neurotrauma on Pressurized Rodent Middle Cerebral Arteries

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爆炸性神经损伤对压生啮鼠中脑动脉的影响

DOI:

10.3791/58792-v

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08:21 min

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April 01, 2019

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Uylissa A. Rodriguez², Yaping Zeng², Margaret A. Parsley², Bridget E. Hawkins², Donald S. Prough², Douglas S. DeWitt²

¹Charles R. Allen Research Laboratories, Department of Anesthesiology,University of Texas Medical Branch, ²The Moody Project for Translational Traumatic Brain Injury Research,University of Texas Medical Branch

Chapters

00:04Title
01:06Advanced Blast Simulator (ABS) Blast Device Preparation
02:06ABS Injury Preparation
03:58Blast-traumatic Brain Injury (TBI) Induction
04:38Rodent Middle Cerebral Artery (MCA) Segment Extraction
07:04Results: Representative Effects of Blast-induced Traumatic Brain Injury (bTBI) on MCA Responses to Reduced Intravascular Pressure
08:00Conclusion

Summary

자동 번역

在这里, 我们提出了一个协议来描述的方法, 在一次爆炸创伤性脑损伤 (bTBI) 后, 使用隔离, 加压, 啮齿类动物中脑动脉 (MCA) 段的体外血管反应性测定。bTBI 感应是使用激波管 (也称为高级爆破模拟器 (ABS) 装置) 完成的。

Tags

Keywords: Blast-induced Neurotrauma Pressurized Rodent Middle Cerebral Arteries Cerebral Vascular Injury Myogenic Vascular Response Isolated Pressurized Arterial Preparation Advanced Blast Simulator Mylar Sheets Hydraulic Hand Pump Anesthetized Rat Endotracheal Tube Ventilator Specimen Tray Heat Lamp Scalp Ear Plug

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