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JoVE Journal Behavior
En mellersta cerebral artär ocklusion teknik för inducera post-stroke depression hos råttor
 
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En mellersta cerebral artär ocklusion teknik för inducera post-stroke depression hos råttor

Article DOI: 10.3791/58875-v • 04:38 min • May 22nd, 2019
May 22nd, 2019 •
*1, *2, 3, 1, 1, 1, 1, 1, 1, 1
1Department of Anesthesiology and Critical Care, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, 2Department of Neurosurgery, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, 3Department of Biophysics and Biochemistry, Faculty of Biology, Ecology, and Medicine, Oles Honchar Dnipro National University
* These authors contributed equally

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Här presenterar vi ett protokoll för att inducera post-stroke depression hos råttor genom ockluding den mellersta cerebral artär via den inre halspulsådern. Vi använder Porsolt tvingade simma test och sackaros preferens test för att bekräfta och utvärdera inducerad depressiva stämningar.

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Beteende ischemisk stroke poststroke depression råtta modell mellersta cerebral artär ocklusion infarct volym hjärnan ödem Porsolt tvingas simma test sackaros preferens test
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