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Engineering

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Assembling Molecular Shuttles Powered by Reversibly Attached Kinesins
 

Assembling Molecular Shuttles Powered by Reversibly Attached Kinesins

Article DOI: 10.3791/59068-v 08:04 min January 26th, 2019
January 26th, 2019

챕터

요약

We present a protocol to build molecular shuttles, where surface-adhered kinesin motor proteins propel dye-labelled microtubules. Weak interactions of the kinesins with the surface enables their reversible attachment to it. This creates a nanoscale system which exhibits dynamic assembly and disassembly of its components while retaining its functionality.

Tags

Keywords: Molecular Shuttles Kinesins Microtubules Nanoscale Biological Systems Self-healing Dynamic Equilibrium Tubulin Paclitaxel Casein ATP Kinesin Motility Solution Flow Cell Coverslips
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