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면역학 및 감염병학

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登革热病毒诱发急性病毒性脑炎样疾病的鼠害模型

JoVE 신문
면역학 및 감염병학

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JoVE 신문 면역학 및 감염병학

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

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登革热病毒诱发急性病毒性脑炎样疾病的鼠害模型

DOI:

10.3791/59132-v

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04:23 min

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April 28, 2019

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Ting-Jing Shen², Ming-Kai Jhan², Jo-Chi Kao², Min-Ru Ho², Tsung-Ting Tsai², Po-Chun Tseng², Yung-Ting Wang², Chiou-Feng Lin^2,3

¹Graduate Institute of Medical Sciences, College of Medicine,Taipei Medical University, ²Department of Microbiology and Immunology, School of Medicine, College of Medicine,Taipei Medical University, ³Center of Infectious Disease and Signaling Research,National Cheng Kung University

Chapters

00:04Title
00:44Infection Procedure and Disease Scoring
02:16Results: Representative Establishment of Mouse Dengue Virus-induced Acute Viral Encephalitis-like Disease
03:06Conclusion

Summary

자동 번역

在这里,我们提出了一个协议,创建一个免疫能力ICR(癌症研究所)的中枢神经系统感染的鼠模型,以显示神经病变的发展。通过相同的疾病评分监测急性病毒性脑病,可以显示体内登革热病毒引起的神经病变。

Tags

Murine Model Dengue Virus Acute Viral Encephalitis Neuropathogenesis Virus Infection Virus Inoculation Disease Progression Body Weight Changes Survival Rates

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