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病原体や医薬品との相互作用、脳によって障壁の交差を勉強する人間の血-脳インターフェイス モデル
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JoVE 신문 신경과학
A Human Blood-Brain Interface Model to Study Barrier Crossings by Pathogens or Medicines and Their Interactions with the Brain
DOI:

07:52 min

April 09, 2019

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Chapters

  • 00:04Title
  • 00:36Human Cerebral Microvascular Endothelial Cell (hCMEC)/D3 Insert Coating and Blood Brain Barrier (BBB) Preparation
  • 02:48BBB-Minibrain Endothelial Permeability Validation
  • 03:38BBB Crossing and Multiplication of Yellow Fever Viruses in the Minibrain and Biomolecule BBB Crossing and Brain Cell Targeting
  • 05:22Results: Representative BBB-Minibrain Testing of Neuroinvasive Variants and Biomolecule Properties
  • 07:19Conclusion

Summary

자동 번역

Cellulo BBB (血液脳関門) の設定を記述したプロトコルをご紹介-Minibrain ポリエステル多孔性膜の文化は人間の BBB にわたって生体分子又は感染性病原体の運搬を評価するためにシステムを挿入、近隣の脳細胞の生理学的な影響は。

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