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骨肉瘤的三维骨细胞外基质模型

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Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

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骨肉瘤的三维骨细胞外基质模型

DOI:

10.3791/59271-v

•

08:07 min

•

April 12, 2019

•

Yu Zhang, Yupeng Yao, Yan Zhang

¹MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences,Sun Yat-sen University

Chapters

00:04Title
00:59Bone Preparation and Demineralization
02:29Bone Decellularization
04:08Cell Seeding and Culture
06:26Results: Characterization of Decellularized BEM and OS Cells
07:44Conclusion

Summary

자동 번역

骨肉瘤 (OS) 的骨细胞外基质 (BEM) 模型已经建立, 并在此进行了展示。它可作为模拟原发肿瘤体外生长的合适支架, 为研究 os 的组织学和细胞生成异质性提供了理想的模型。

Tags

Keywords: 3D Bone Extracellular Matrix Osteosarcoma Decellularization Bone-derived Matrix Bone Tumor Research Heterogenous Morphology Drug Sensitivity Ewing Sarcoma Metastatic Bone Tumors BALB/c Mice Bone Decalcification Lipid Extraction

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