Waiting
로그인 처리 중...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Modified Heterotopic Hindlimb Osteomyocutaneous…
JoVE Journal
Medicine

JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.

JoVE Journal Medicine
Modified Heterotopic Hindlimb Osteomyocutaneous Flap Model in the Rat for Translational Vascularized Composite Allotransplantation Research
 

Modified Heterotopic Hindlimb Osteomyocutaneous Flap Model in the Rat for Translational Vascularized Composite Allotransplantation Research

Article DOI: 10.3791/59458-v • 09:36 min • April 26th, 2019
April 26th, 2019 •
1, 2,3, 2,3, 2,4, 2,4, 1, 2,4
1Christine M. Kleinert Institute for Hand and Microsurgery, 2Cardiovascular Innovation Institute, University of Louisville, 3Kentucky Spinal Cord Injury Research Center, University of Louisville, 4Department of Physiology, University of Louisville

챕터

요약
Automatic Translation

Vascularized composite allograft offers life-altering benefits to transplant recipients, but the biological causes of graft rejection and vasculopathy remain poorly understood. The rodent surgical model presented here offers a reproducible, clinically relevant model of transplantation, allowing researchers to evaluate rejection events and potential therapeutic strategies to prevent their occurrence.

Tags

Keywords: Vascularized Composite Allotransplantation Hindlimb Osteomyocutaneous Flap Rat Model Vasculopathy Graft Rejection Macrovascular Surgical Techniques Ischemic Damage Skin Muscle Bone Orthotopic Models Hand Transplant Donor Vessels Recipient Surgical Site Inguinal Pocket
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter