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Inducing Apical Periodontitis in Mice
JoVE 신문
생물학
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JoVE 신문 생물학
Inducing Apical Periodontitis in Mice
DOI:

10:26 min

August 06, 2019

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Chapters

  • 00:04Title
  • 00:48Animal Preparation
  • 01:49Pulp Exposure
  • 03:04Post Procedure Follow-Up and Experiment Termination
  • 04:18Micro-Computed Tomography (Micro-CT)
  • 05:42Contouring
  • 06:54Histology
  • 08:27Results: Representative Micro-CT and Histological Analyses
  • 09:41Conclusion

Summary

자동 번역

Here, we present a protocol to locally induce apical periodontitis in mice. We show how to drill a hole in the mouse's tooth and expose its pulp, in order to cause local inflammation. Analysis methods to investigate the nature of this inflammation, such as micro-CT and histology, are also demonstrated.

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