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Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
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Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

DOI:
10.3791/59666-v

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06:09 min

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June 07, 2019

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, , , ,
1Department of Biomedical Sciences,Cornell University

Chapters

  • 00:04Title
  • 00:35Skin Preparation and Ultraviolet (UV)-B Irradiation
  • 01:39Skin Isolation
  • 02:29Tissue Fixation
  • 03:06Frozen Tissue Block Preparation
  • 04:15Results: Representative Spatial and Temporal Control of Murine Melanoma Initiation
  • 05:50Conclusion

Summary

자동 번역

자동 번역

The following procedure describes a method for spatial and temporal control of melanocytic tumor initiation in murine dorsal skin, using a genetically engineered mouse model. This protocol describes macroscopic as well as microscopic cutaneous melanoma initiation.

Tags

Keywords: Spatial ControlTemporal ControlMurine MelanomaMelanocyte Stem CellsMelanoma InitiationUV-B IrradiationSample Preparation

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