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Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury
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Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury

Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury

DOI:
10.3791/59748-v

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00:05 min

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August 30, 2019

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,
1Department of Surgery,University of Pittsburgh

Chapters

  • 00:04Title
  • 00:50Tumor Cell Injection
  • 02:37Ischemia and Reperfusion Injury
  • 04:27Splenectomy
  • 05:06Results: Representative Micrometastasis Evaluation After Murine Tumor Cell Injection
  • 05:28Conclusion

Summary

자동 번역

자동 번역

We describe in detail a clinically relevant colorectal cancer liver metastases (CRLM) tumor model and the influence of liver ischemia reperfusion (I/R) in tumor growth and metastasis. This model can help to better understand the mechanisms underlying surgery-induced promotion of liver metastatic growth.

Tags

Keywords: Murine ModelMetastatic Liver TumorsIschemia Reperfusion InjuryLiver SurgeryCancer Cell InjectionSpleenPortal VeinLiver LobesIschemia Reperfusion

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