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Un método para estudiar la formación de novo de dominios de cromatina
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JoVE 신문 유전학
A Method to Study de novo Formation of Chromatin Domains
DOI:

00:07 min

August 23, 2019

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Chapters

  • 00:04Title
  • 00:37Generation of Clonal EED Knockout Mouse Embryonic Stem Cells
  • 02:51Engineering Cre-ERT2 Based Inducible EED Expression
  • 04:11Following Nucleation and Spreading of PRC2 Activity on Chromatin
  • 05:10Results: Validations and Representative Applications of Inducible EED Rescue Systems
  • 06:43Conclusion

Summary

자동 번역

Este método está diseñado para seguir la formación de dominios de cromatina mediadas por PRC2 en líneas celulares, y el método se puede adaptar a muchos otros sistemas.

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