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Semi-Minimal Invasive Method to Induce Myocardial Infarction in Rats and the Assessment of Cardiac Function by an Isolated Working Heart System
 

Semi-Minimal Invasive Method to Induce Myocardial Infarction in Rats and the Assessment of Cardiac Function by an Isolated Working Heart System

Article DOI: 10.3791/61033-v • 08:01 min • June 11th, 2020
June 11th, 2020 •
1, 1, 1, 1, 1, 1, 2, 3, 1, 1
1Ludwig-Boltzmann-Institute for Cardiovascular Research at the Center for Biomedical Research, Medical University of Vienna, 2Concept & Ideation, Electrical Sector/EMEA/Power Distribution Division, Eaton Industries (Austria) GmbH, 3Vetfarm and Clinical Unit for Herd Health Management in Ruminants, Clinic for Ruminants, Vetmeduni Vienna

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요약
Automatic Translation

This article presents an efficient method to perform myocardial ischemia and subsequent chronic reperfusion in rats using a minimally invasive approach. In addition, left ventricular hemodynamic function of rats is assessed by echocardiography and isolated working heart methods. 

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Keywords: Myocardial Infarction Rat Model Semi-minimal Invasive Isolated Working Heart System Left Anterior Descending Artery Occlusion Ischemia-reperfusion Cardiac Function Assessment
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