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肾动脉狭窄肾素调节的改良双肾单夹小鼠模型

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A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis

Please note that all translations are automatically generated. Click here for the English version.

肾动脉狭窄肾素调节的改良双肾单夹小鼠模型

DOI:

10.3791/61058-v

•

08:21 min

•

October 26, 2020

•

Mohammad Saleem, Pierina Barturen-Larrea, Luz Saavedra, Jose A. Gomez

¹Department of Medicine/Clinical Pharmacology Division,Vanderbilt University Medical Center

Chapters

00:05Introduction
01:22Animal Preparation and Dissection
03:21Right Renal Artery Stenosis
04:42Tissue Harvest
06:04Results: Renin Expression after Renal Artery Stenosis
07:52Conclusion

Summary

자동 번역

使用聚氨酯管开发改良的2肾1夹（2K1C）Goldblatt小鼠模型以启动肾动脉狭窄，诱导肾素表达增加和肾损伤。在这里，我们描述了准备袖带并将其置于肾动脉上以产生可重复且一致的2K1C小鼠模型的详细程序。

Tags

Keywords: 2K1C Mouse Model Renal Artery Stenosis Renin Regulation Renal Vascular Hypertension Polyurethane Tubing Renal Artery Constriction Surgical Procedure Mouse Surgery Anesthesia Renal Artery Isolation Renal Nerve Isolation

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