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双直接注射血液到西斯特纳麦格作为苏巴拉奇内德出血的模型
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Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
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双直接注射血液到西斯特纳麦格作为苏巴拉奇内德出血的模型

DOI:
10.3791/61322-v

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10:34 min

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August 30, 2020

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, , , ,
1University of Rouen Normandy, INSERM U1239, DC2N, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France, 2Department of Anesthesiology and Critical Care,Rouen University Hospital, Rouen, France

Chapters

  • 00:00Introduction
  • 02:07Procedure: Setup of SAH Surgery
  • 02:47Procedure: Collection of Blood from a Homologous Mouse Donor
  • 03:25Procedure: Animal Preparation
  • 04:21Procedure: SAH Induction
  • 06:18Post-surgery Procedure
  • 06:42Second Day of Surgery
  • 07:38Representative Results
  • 09:51Conclusion

Summary

자동 번역

자동 번역

我们在该协议中描述了一个标准化的亚巴纳内出血 （SAH） 小鼠模型，通过双注射自体全血到 cisterna 磁石。双注射程序高度标准化，代表了在死亡率方面相对安全性的SAH中急性模型。

Tags

Subarachnoid HemorrhageDouble Direct InjectionCisterna MagnaAneurysmCerebral IschemiaVasospasmAnimal ModelAutologous Arterial BloodNoninvasive Surgical ProcedureIntracranial Pressure

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