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1Division of Neonatology, Stead Family Department of Pediatrics,University of Iowa, 2Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology,University of Iowa, 3Division of Neonatology, Department of Pediatrics,Vanderbilt University, 4Department of Microbiology & Immunology,University of Iowa
Chapters
- 00:04Introduction
- 00:52Establishment of FEMI in Pregnant Mice
- 02:06Delivery and Care of Offspring and Intestinal Harvesting
- 03:03Intestinal Injury Scoring
- 04:11Quantification of Paneth and Goblet Cells
- 06:35Results: Intestinal Injury of Newborn Mice Induced by FEMI
- 08:22Conclusion
Desarrollamos un modelo de coleamnionitis para simular la exposición fetal a la inflamación materna (FEMI) sin complicaciones de organismos vivos para examinar los efectos del FEMI en el desarrollo del tracto intestinal de la descendencia. Esto permite el estudio de causas mecanicistas para el desarrollo de lesiones intestinales después de la coleamnionitis.
