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En In Vitro Hemodynamic Loop Model til at undersøge Hæmocytocompatibility og Host Cell Aktivering af vaskulære medicinsk udstyr
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An In Vitro Hemodynamic Loop Model to Investigate the Hemocytocompatibility and Host Cell Activation of Vascular Medical Devices

En In Vitro Hemodynamic Loop Model til at undersøge Hæmocytocompatibility og Host Cell Aktivering af vaskulære medicinsk udstyr

DOI:
10.3791/61570-v

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08:44 min

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August 21, 2020

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, , , , , , , , ,
1Department of Cardiothoracic Surgery,Otto-von-Guericke-University, 2Department of Mechanical Engineering, Institute for Materials and Joining Technology,Otto-von-Guericke-University, 3Institute of Clinical Chemistry and Pathobiochemistry,Otto-von-Guericke-University, 4Division of Cardiology and Angiology, Department of Internal Medicine,Otto-von-Guericke-University

Chapters

  • 00:04Introduction
  • 00:43In Vitro Hemodynamic Loop Assembly and Blood Collection
  • 02:59Blood Sample Processing and Scanning Electron Microscopy (SEM) and Microcomputed Tomography (CT) Imaging Preparation
  • 04:16Flow Cytometry
  • 06:12Results: Representative Hemocytocompatibility and Host Cell Activation Analyses
  • 08:09Conclusion

Summary

자동 번역

자동 번역

Præsenteret her er en protokol for en standardiseret in vitro hæmodynamisk loop model. Denne model gør det muligt at teste hæmokompatibilitet af perfusion rør eller vaskulære stents at være i overensstemmelse med ISO (International Organization for Standardisering) standard 10993-4.

Tags

Keywords: In Vitro Hemodynamic Loop ModelHemocytocompatibilityHost Cell ActivationVascular Medical DevicesPerfusion TubingsStentsBlood CompatibilityTube CutterTension Band ConnectorStent Loop AssemblyLoop CradleRotation UnitHeparinBlood CollectionHomogenous SolutionBlood FillingLoop Rotation

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